Antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions and are becoming the molecules of choice for further combination therapies and cell engineering. Current developments and clinical successes are summarised by experts in the drug development field. A must read for immunologists, clinical scientists and novel drug developers.

Historical Development of Monoclonal Antibody Therapeutics

Preclinical Safety Evaluation of Monoclonal Antibodies
Molecular Developments in Antibody Production
Engineering Antibodies for Stability and Efficient Folding
Human Monoclonal Antibodies from Transgenic Mice
Antibodies to Cytokines
Anti-TNF Antibodies: Lessons from the Past, Roadmap for the Future
Therapeutic Anti-VEGF Antibodies
Humanized Antihuman IL-6 Receptor Antibody, Tocilizumab
Antibodies to Cell Markers
Anti-CD20Monoclonal Antibody in Rheumatoid Arthritis and Systemic Lupus Erythematosus
Herceptin
The Use of CD3-Specific Antibodies in Autoimmune Diabetes: A Step Toward the Induction of Immune Tolerance in the Clinic
Monoclonal Antibody Therapy for Prostate Cancer
Anti-IgE and Other Antibody Targets in Asthma
Development of Antibody-Based Cellular and Molecular Therapies
Cytokine, Chemokine, and Co-Stimulatory Fusion Proteins for the Immunotherapy of Solid Tumors
The T-Body Approach: Redirecting T Cells with Antibody Specificity
Intracellular Antibodies (Intrabodies) and Their Therapeutic Potential.