Thymic Development and Selection of T Lymphocytes
E-Book
Thymic Development and Selection of T Lymphocytes
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
| ISBN | 9783642402524 |
|---|---|
| Artikelnummer | 9783642402524 |
| Medientyp | E-Book - PDF |
| Auflage | 2. Aufl. |
| Copyrightjahr | 2013 |
| Verlag | Springer-Verlag |
| Umfang | 132 Seiten |
| Sprache | Englisch |
| Kopierschutz | Digitales Wasserzeichen |
