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This textbook covers the main tools and techniques used in bioanalysis, provides an overview of their principles, and offers several examples of their application and future trends in diagnosis.

Chapters from expert contributors explore the role of bioanalysis in different areas such as biochemistry, physiology, forensics, and clinical diagnosis, including topics from sampling/sample preparation, chemometrics in bioanalysis to the latest techniques used in the field. Particular attention is given to the recent advances in the application of mass spectrometry, NMR, electrochemical methods and separation techniques in bioanalysis. Readers will also find more about the application of microchip-based devices and analytical microarrays.

This textbook will appeal to graduate/advanced undergraduate students in Chemistry, Biology, Biochemistry, Pharmacy, and Chemical Engineering. It is also a useful resource for researchers and professionals working in the fields of biomedicine and veterinary sciences, with clear explanations and examples of how the different bioanalytical devices are applied for clinical diagnosis.



What is bioanalytical chemistry? Scientific opportunities with immediate impact
Role of bioanalytical chemistry in the 21st century
Sampling and sample preparation in bioanalysis
UV-VIS absorption and fluorescence in bioanalysis
High-resolution techniques based on atomic and emission spectrometry applied to bioanalytical purposes
Vibrational spectroscopy in bioanalysis
Biological systems investigated by smal-angle X-ray scattering
High resolution optical fluorescence microscopy for cell biology studies
Nuclear magnetic resonance spectroscopy in analyses of biological samples
SPR sensors: From configurations to bioanalytical applications
Introduction to electroanalysis
Amperometric detection for bioanalysis
Potentiometric biosensors
Electrochemical methods applied for bioanalysis. Differential pulse voltammetry and square wave voltammetry
Impedimetric immunosensors for clinical practices: Focus on point-of-care diagnostics
Organic electrochemical transistors in bioanalytical chemistry
Quartz crystal microbalance in bioanalysis
Scanning electrochemical microscopy (SECM): Fundamentals and applications
Modified electrodes surface with inorganic oxides and conducting polymers
The role of gas chromatography in bioanalysis.- Liquid chromatography in bioanalysis
The role of capillary electromigration separation techniques in bioanalysis
Introduction to bioanalytical mass spectrometry
Microchip-based devices for bioanalytical applications
Microarrays application in life sciences - The beginning of the revolution
Chemometrics in bioanalytical chemistry
Recent advances and future trends in bioanalytical chemistry.

ISBN 978-3-030-82383-2
Artikelnummer 9783030823832
Medientyp Buch
Auflage 1st ed. 2022
Copyrightjahr 2022
Verlag Springer, Berlin
Umfang XIII, 558 Seiten
Abbildungen XIII, 558 p. 143 illus., 127 illus. in color.
Sprache Englisch