Total Chemical Synthesis of Proteins

Total Chemical Synthesis of Proteins

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With contributions from a panel of experts representing a range of disciplines, this practical reference presents a carefully curated collection of synthetic approaches and strategies for the total synthesis of native and modified proteins.

Characterization of protein molecules prepared by total chemical synthesis
Automated fast flow peptide synthesis
N,S- and N,Se-acyl transfer devices in protein synthesis
Chemical synthesis of proteins through native chemical ligation of peptide hydrazides
Expanding native chemical ligation methodology with synthetic amino acid derivatives
Peptide ligations at sterically demanding sites
Controlling segment solubility in large protein synthesis
Towards HPLC-free total chemical synthesis of proteins
Solid phase chemical ligation
Ser/Thr ligation for protein chemical synthesis
Protein semisynthesis
Bio-orthogonal imine chemistry in chemical protein synthesis
Deciphering protein folding using chemical protein synthesis
Chemical synthesis of ubiquitinated proteins for biochemical studies
Glycoprotein synthesis
Chemical Synthesis of membrane proteins
Chemical synthesis of selenoproteins
Histone synthesis
Application of chemical synthesis to engineer protein backbone connectivity
Beyond phosphate esters - synthesis of unusually phosphorylated peptides and proteins for proteomic research
Cyclic peptides via ligation methods
ISBN 9783527346608
Artikelnummer 9783527346608
Medientyp Buch
Auflage 1. Auflage
Copyrightjahr 2021
Verlag Wiley-VCH
Umfang XX, 604 Seiten
Abbildungen 200 SW-Abb., 100 Farbabb.
Sprache Englisch