Total Chemical Synthesis of Proteins

Total Chemical Synthesis of Proteins

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With contributions from a panel of experts representing a range of disciplines, this practical reference presents a carefully curated collection of synthetic approaches and strategies for the total synthesis of native and modified proteins.

Characterization of protein molecules prepared by total chemical synthesis <br>Automated fast flow peptide synthesis<br>N,S- and N,Se-acyl transfer devices in protein synthesis<br>Chemical synthesis of proteins through native chemical ligation of peptide hydrazides<br>Expanding native chemical ligation methodology with synthetic amino acid derivatives<br>Peptide ligations at sterically demanding sites<br>Controlling segment solubility in large protein synthesis<br>Towards HPLC-free total chemical synthesis of proteins<br>Solid phase chemical ligation<br>Ser/Thr ligation for protein chemical synthesis<br>Protein semisynthesis <br>Bio-orthogonal imine chemistry in chemical protein synthesis<br>Deciphering protein folding using chemical protein synthesis<br>Chemical synthesis of ubiquitinated proteins for biochemical studies<br>Glycoprotein synthesis<br>Chemical Synthesis of membrane proteins <br>Chemical synthesis of selenoproteins <br>Histone synthesis<br>Application of chemical synthesis to engineer protein backbone connectivity<br>Beyond phosphate esters - synthesis of unusually phosphorylated peptides and proteins for proteomic research<br>Cyclic peptides via ligation methods
ISBN 9783527346608
Artikelnummer 9783527346608
Medientyp Buch
Auflage 1. Auflage
Copyrightjahr 2021
Verlag Wiley-VCH
Umfang XX, 604 Seiten
Abbildungen 200 SW-Abb., 100 Farbabb.
Sprache Englisch