Total Synthesis of (±)-Maoecrystal V
Total Synthesis of (±)-Maoecrystal V
In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel and concise approach for the stereo selective construction of the tetracyclic model system of Maoecrystal V. The model system is accomplished in 8 steps with 20% yield. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton. The total synthesis starts from a known compound and is accomplished in 17 steps with 1.2% yield. The successful total synthesis of Maoecrystal V will contribute to the development of efficient synthetic strategies for natural products and other compounds with complex structures.
The total synthesis study of Maoecrystal V
Summary.
Research Background for Natural Product Maoecrystal V and Its Family
The Model Study of Natural Product Maoecrystal VThe total synthesis study of Maoecrystal V
Summary.
Gong, Jianxian
ISBN | 978-3-642-54303-6 |
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Artikelnummer | 9783642543036 |
Medientyp | Buch |
Auflage | 2014 |
Copyrightjahr | 2014 |
Verlag | Springer, Berlin |
Umfang | XII, 137 Seiten |
Abbildungen | XII, 137 p. 177 illus., 1 illus. in color. |
Sprache | Englisch |