This book presents both theoretical and practical aspects of transbronchial cryobiopsy, a new diagnostic technique for the detection of diffuse parenchymal lung disease that is attracting great interest in the scientific community. In the context of a multidisciplinary discussion, comprising radiologic-pathologic correlations, the authors examine the technical and safety issues - such as equipment, endoscopic setting, anesthesiologic approaches and bleeding control - on one hand, and the diagnostic yield and clinical meaning on the other.

The volume offers several case studies - including idiopathic pulmonary fibrosis, granulomatous disorders, interstitial pneumonias, rare lung disseminated tumors- that illustrate the high diagnostic yield and safety of this innovative technique. The book appeals to a wide readership, including residents, pulmonologists with expertise in diffuse parenchymal lung diseases, interventional pulmonologists, thoracic radiologists, pathologists, anesthesiologists, internists and rheumatologists.

<p>I Introduction to Diffuse Parenchimal Lung Disease

1 Diffuse Parenchymal Lung Disease: A Clinical Overview
2 Radiologic-pathologic Correlations in Diffuse Parenchymal Lung Disease
3 Multidisciplinary discussion in Diffuse Parenchymal Lung Disease
II Transbronchial cryobiopsy
4 Cryobiopsy: Physics
5 Cryobiopsy: How it Happened
6 Technique and equipment in Transbronchial Cryobiopsy
7 Complications in Transbronchial Cryobiopsy
8 Immunohystochemistry and Molecular Biology in Transbronchial Cryobiopsy
III Clinical role of Transbronchial Cryobiopsy
9 The Diagnostic Yield of Transbronchial Cryobiopsy
10 Clinical Meaning of Transbronchial Cryobiopsy
11 Pathologic considerations in Transbronchial Cryobiopsy
12 Future perspectives for Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Disease
IV Case series
13 Idiopahic Pulmonary Fibrosis
14 Chronic hypersensitivity pneumonitis
15 Other granulomatoses
16 Nonspecific interstitial pneumonia
17 Collagenvascular diseases
18 Smoking related ILDs
19 Lymphangioleiomyomatosis
20 Pleuroparenchymal fibroelastosis
21 Acute lung injury
22 Neoplasms
23 Rarities.</p><p></p>