In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field have written 35 essays which describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs, from pharmacologists and physiologists to medical doctors, other scientists, students and lecturers. It fills a gap between pharmacology textbooks and latest manuscripts in scientific periodicals.

An Introduction on TRP Channels

An Introduction on TRP Channels
TRPC Channel Subfamily
TRPC1 Ca2+-Permeable Channels in Animal Cells
TRPC2: Molecular Biology and Functional Importance
TRPC3: A Multifunctional, Pore-Forming Signalling Molecule
Ionic Channels Formed by TRPC4
Canonical Transient Receptor Potential 5
TRPC6
TRPC7
TRPV Channel Subfamily
Capsaicin Receptor: TRPV1 A Promiscuous TRP Channel
2-Aminoethoxydiphenyl Borate as a Common Activator of TRPV1, TRPV2, and TRPV3 Channels
TRPV4
TRPV5, the Gateway to Ca2+ Homeostasis
TRPV6
TRPM Channel Subfamily
TRPM2
TRPM3
Insights into TRPM4 Function, Regulation and Physiological Role
TRPM5 and Taste Transduction
TRPM6: A Janus-Like Protein
The Mg2+ and Mg2+-Nucleotide-Regulated Channel-Kinase TRPM7
TRPM8
Other TRP Channels
TRPA1
TRPP2 Channel Regulation
TRP Proteins and Specific Cellular Functions
Know Thy Neighbor: A Survey of Diseases and Complex Syndromes that Map to Chromosomal Regions Encoding TRP Channels
TRP Channels of the Pancreatic Beta Cell
TRP Channels in Platelet Function
TRP Channels in Lymphocytes
Link Between TRPV Channels and Mast Cell Function
TRPV Channels' Role in Osmotransduction and Mechanotransduction
Nociception and TRP Channels
TRP Proteins - Integrators of Multiple Inputs
Regulation of TRP Ion Channels by Phosphatidylinositol-4,5-Bisphosphate
TRPC, cGMP-Dependent Protein Kinases and Cytosolic Ca2+
Trafficking of TRP Channels: Determinants of Channel Function
TRPC Channels: Interacting Proteins
TRPC Channels: Integrators of Multiple Cellular Signals
Phospholipase C-Coupled Receptors and Activation of TRPC Channels
Erratum
Erratum.