Hematopoietic stem cell and immune cell transplantation has cont- ued as a promising therapeutic alternative and a fascinating area of cell biology as well as a field of persistent procedural problems. This - plains why substantial parts of basic research on cell growth and d- ferentiation, immune tolerance and antitumor effects, gene transfer, minimal residual disease and supportive care have settled around cli- cal transplantation in hematology and oncology. This second volume again updates the current role of allogeneic and autologous transpl- tation in leukemias, lymphomas and solid cancers, including cont- versial strategies and novel experimental approaches. In particular, cellular immune therapy, new conditioning strategies, mismatched donor transplantation, updated clinical transplantation, antiangiogenesis and strategies against fungal infections are focused upon. Outstanding representatives of leading groups guarantee fir- hand information and indicate how we can work and cooperate more effectively to the benefit of our patients. The editors are indebted to the Gesellschaft zur Bekämpfung der Krebskrankheiten Nordrhein-Westfalen for a substantial support of the publication. They also acknowledge the major contribution of Beate Kosel as coordinator of the editorial work.

Cellular Therapy: Targets and Effectors

Adoptive Immunotherapy in Chimeras
The Roles of the Chemokine SDF-1 and its Receptor CXCR4 in Human Stem Cell Migration and Repopulation of NOD/SCID and B2mnull NOD/SCID mice
Towards Adoptive Immunotherapy Using High Affinity T Cell Receptors
New Antigens and Avenues to Immunotherapy of Cancer
Allogeneic Cell Therapy with Antigen-Specific Cytotoxic T Lymphocytes (CTL) for Malignant Melanoma
New Conditioning Strategies n Allogeneic Stem Cell Transplantation
Intensification of the Conditioning Regimen for Patients with high-risk AML and MDS: 3 year Experience of using an188 Re - Labelled anti - CD 66 Monoclonal Antibody
Dose Reduced Conditioning for Allogeneic Blood Stem Cell Transplantation from Sibling and Unrelated Donors in 51 Patients
Pharmacokinetics of Conditioning Regimens
Megadose Stem Cell Transplantation
HD-Ara-C in the Conditioning Regimen for BMT in Acute Leukemias
TBI-Based Reduced Intensity Conditioning with Allogeneic Hematopoietic Stem Cell Transplantation (SCT) in Patients with High-Risk Hematologic Malignancies
Total Marrow Irradation (TMI), Busulfan, and Cyclophos-phamide for Allografting in Multiple Myeloma. A Pilot Study
Stem Cell Mobilisation, Processing and Characteristics
A "Single" Delayed Application of G-CSF after Autologous Peripheral Blood Stem Cell Transplantation - A Pilot Study
Factors Influencing PBPC Mobilisation and Collection in Haematological Malignancies
Successful Purging of Stem Cell Products Using CD34 Selection
Autologous Transplantation of Non-Cryopreserved HSCs in Oncologic Patients with Poor Prognosis: First Experience in the Ukraine
A Randomized Comparison of Once Versus Twice Daily rhG-CSF (Filgrastim) for Stem Cell Mobilisation in Healthy Donors for Allogeneic Transplantation
CD 133/CD34 Expression on Hematopoietic Stem-/ Progenitor Cells and Acute Leukemic Blasts
Identification of Minimal Residual Leukemia Applying Continuous Gating
Cord Blood Transplantation
Pilot Study - Lymphocyte Subset Reconstitution after Cord Blood Transplantation
Altered Growth Characteristics of Cord Blood after in vivo Exposure of the Mother to Chemotherapy
Mismatched Donor Transplantation
Bone Marrow Transplantation from Mismatched Unrelated Donors
Immune Reconstitution after Haploidentical Stem Cell Transplantation
Clinical Transplantation - Hematologic Malignancies
Autografting and Allografting for Chronic Lymphocytic Leukemia: Is there a Rationale?
Results of Stem Cell Transplantation in Children with CML in Comparison with Treatment with Cytostatics alone or with Interferon alfa. Report of the Polish Children's Leukemia/Lymphoma Study Group
Comparison of Allogeneic Matched Related Stem Cell Transplantation in 1st CR with Chemotherapy alone in Children with High-Risk AML
Stem Cell Transplantation in Acute Myeloid Leukemia after Conditioning with Busulfan, Cyclophosphamide and Different Dosages of Etoposide (VP-16)
The Occurrence of Acute Graft-Versus-Host Disease and Infectious Complications in Patients with Acute and Chronic Myeloid Leukemia who Underwent Allogeneic Peripheral Blood Stem Cell Transplantation
Long-Term Survival after Stem Cell Transplant in Adult Acute Lymphoblastic Leukemia
Clinical Transplantation - Solid Tumors
Autologous Transplantation in Breast Cancer in Europe and EBMT Data
First-Line and Salvage High-Dose Chemotherapy in Patients with Germ-Cell Tumors
High Dose Chemotherapy in High-Risk Ewing Tumours: Results in 156 (EI)CESS Patients
Rapid Sequence Tandem Transplant in Children with High-Risk Neuroblastoma
Anti-Angiogenesis
Angiogenesis Inhibitor TNP-470 During Bone Marrow Transplant and in Minimal Residual Disease
Challenges in the Treatment of Fungal Infections
Prophylaxis of Fungal Infections in Neutropenic Patients with Hematologic Malignancies.