1;Contents;5 2;List of Contributors;16 3;Part I Diagnostics;22 3.1;Biopsy of Bone and Soft Tissue Tumours: Hints and Hazards;23 3.2;The Role of Intra- operative Pathological Evaluation in the Management of Musculoskeletal Tumours;31 3.3;Sentinel Node Biopsy in Soft Tissue Sarcoma;45 4;Part II Bone Sarcomas;57 4.1;Modular Endoprosthetic Reconstruction in Malignant Bone Tumors: Indications and Limits;58 4.2;Allograft Reconstruction in Malignant Bone Tumors: Indications and Limits;70 4.3;Expandable Endoprostheses in Malignant Bone Tumors in Children: Indications and Limitations;78 4.4;The Long-Term Risks of Infection and Amputation with Limb Salvage Surgery Using Endoprostheses;93 4.5;Reconstruction of the Pelvis After Resection of Malignant Bone Tumours in Children and Adolescents;103 4.6;Methods of Biological Reconstruction for Bone Sarcoma: Indications and Limits;130 4.7;Bone Sarcoma of the Spine;158 4.8;Computer- Assisted Pelvic Tumor Resection: Fields of Application, Limits, and Perspectives;185 4.9;Pulmonary Metastasectomy for Osteosarcoma: Is It Justified?;199 5;Part III Soft Tissue Sarcomas;225 5.1;Standardized Approach to the Treatment of Adult Soft Tissue Sarcoma of the Extremities;226 5.2;Evaluating Surgery Quality in Soft Tissue Sarcoma;244 5.3;Peripheral Nerve Considerations in the Management of Extremity Soft Tissue Sarcomas;258 5.4;Isolated Limb Perfusion with TNF- a and Melphalan in Locally Advanced Soft Tissue Sarcomas of the Extremities;272 5.5;Management of Locally Recurrent Soft Tissue Sarcoma after Prior Surgery and Radiation Therapy;286 5.6;Management of Vascular Involvement in Extremity Soft Tissue Sarcoma;299 5.7;Current Concepts in the Management of Retroperitoneal Soft Tissue Sarcoma;314 5.8;Pulmonary Metastasectomy for Soft Tissue Sarcomas: Is It Justified?;333 6;Part IV Quality of Life Assessment;349 6.1;Quality of Life ( QOL) in Patients with Osteosarcoma;350 6.2;Clinical Trials in Osteosarcoma Treatment: Patients' Perspective Through Art;356