This book is targeted at ensuring frontline clinical staff including seniors, trainees and specialist nurses can easily reference the optimum investigation and management of potential TB cases. This will mirror the annual London Advanced TB course which aims to equip all of the team delivering care to have a working knowledge of the entire spectrum of the real life aspects of TB management ranging from investigation of active TB to latent screening in pre biologic therapy. It includes an update of MDR TB management and also the approaches needed to ensure the entire medico-social spectrum of TB care is addressed.

Trends in TB epidemiology

Natural History of TB and latent TB
The BCG vaccine
Contact tracing and screening new entrants - science, rationale and progress
Pulmonary, Pleural and Mediastinal TB - clinical aspects and diagnosis
Lymph Node/ Abdominal/ Renal /Pericardial TB - clinical aspects, diagnosis and managing paradoxical reactions
Radiology of TB
Routine Laboratory Diagnostic Techniques
TB and HIV issues
Spinal and Bone TB
CNS and Meningeal TB - management
Molecular tools - current and future applications in the reference laboratory
Therapeutic Drug Monitoring
MDR TB Management
The interferon gamma release assays - science and rationale
TB in renal disease
Anti-TNF, immunosuppression approaches in TB
Occupational Health Screening
Infection Control
Supporting the Hard to Reach
Incident Management and 'Mass screening'
Paediatric TB Issues
TB treatment and complications
A Global TB Overview.<p></p>