Tumor-Associated Antigens

Identification, Characterization, and Clinical Applications

Tumor-Associated Antigens

Identification, Characterization, and Clinical Applications

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The first comprehensive and most recent overview of the topic, this ready reference and handbook reviews current knowledge of TAAs, their subclasses, and pinpoints their application areas in medicine. In addition, it emphasizes target identification procedures, the need for an accurate and thorough analysis of the function of TAAs, and the validation of those in clinical settings. The whole is rounded off with an overview of currently approved therapeutic antibodies.
The result is a must-have for biologists and oncologists in science, clinics and industry.

Olivier Gires is a group leader at the ENT research department, Munich Medical Center, Germany and leading head of the Clinical Cooperation Group Molecular Oncology at the GSF. In 1999, he obtained his PhD in biology for his work on Epstein-Barr virus' oncoprotein LMP1. Thereafter, Olivier Gires focused on the identification and molecular characterization of tumor-associated antigens with particular emphasis on the elucidation of the function of the therapeutic target EpCAM. Work by his group unraveled the oncogenic potential of EpCAM along with underlying molecular mechanisms. Additionally, he was decisively involved in the development of the target identification technology AMIDA.
ISBN 9783527625987
Artikelnummer 9783527625987
Medientyp E-Book - PDF
Copyrightjahr 2009
Verlag Wiley-Blackwell
Umfang 383 Seiten
Sprache Englisch
Kopierschutz Adobe DRM