Despite ongoing progress in nano- and biomaterial sciences, large scale bioprocessing of nanoparticles remains a great challenge, especially because of the difficulties in removing unwanted elements during processing in food, pharmaceutical and feed industry at production level. This book presents magnetic nanoparticles and a novel technology for the upscaling of protein separation. The results come from the EU Project "MagPro2Life", which was conducted in cooperation of several european institutions and companies.

Introduction

Part I: Particle Synthesis and Functionalization
New Advances in the Production of Iron-Based Nanostructures by Laser Pyrolysis
Chemical Coprecipitation for Hydrophobic and Hydrophilic Magnetite Nanoparticles
Magnetic Microgels: Synthesis and Characterization
Vesicles and Composite Particles by Rotating Membrane Pore Extrusion
Synthesis of Functionalized Magnetic Beads Using Spray Drying
Industrial Production, Surface Modification and Application of Magnetic Particles
Part II: Magnetic Separation Devices
Magneticall Enhanced Centrifugation for Industrial Use
Design and Performance of a Pilot Scale High-Gradient Magnetic Filter using a Mandhala Magnet and its Application for Soy-Whey Protein Purification
Continuous Magnetic Extraction for Protein Purification
Part III: Process examples
In-situ Magnetic Separation of Pilot Scale : A Tool for Process Optimization
An Industrial Approach to High-Gradient Magnetic Filtration in the Food Industry
Conclusion.