Vaccines for Pandemic Influenza
E-Book
Vaccines for Pandemic Influenza
The recent outbreak of disease caused by a novel H1N1 virus has focused global attention on the threat of a new influenza pandemic. Recent years have also seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans resulting in numerous fatalities. The rapid expansion in the geographic distribution of these novel viruses raises the risk that such a virus could cause a global pandemic with high morbidity and mortality.
1;Preface;62;Contents;103;Contributors;134;Part I Pandemic Influenza Overview;194.1;Pandemic Influenza as a Current Threat;204.2;Antigenic Cross-Reactivity Among H5N1 Viruses;425;Part II Current Approaches for Human and Avian Vaccine Production;585.1;Seasonal Influenza Vaccines;595.2;Generation and Characterization of Candidate Vaccine Viruses for Prepandemic Influenza Vaccines;995.3;Live Attenuated Vaccines for Pandemic Influenza;1255.4;Influenza Vaccines for Avian Species;1495.5;Development and Application of Avian Influenza Vaccines in China;1696;Part III Novel Vaccine Approaches;1796.1;Designing Vaccines for Pandemic Influenza;1806.2;Attenuated Influenza Virus Vaccines with Modified NS1 Proteins;1926.3;DNA Vaccines Against Influenza Viruses;2116.4;Recombinant Proteins Produced in Insect Cells;2256.5;Influenza Neuraminidase as a Vaccine Antigen;2406.6;Recombinant Vectors as Influenza Vaccines;2556.7;Influenza Virus-Like Particles as Pandemic Vaccines;2806.8;Pandemic Influenza Vaccines;3016.9;Adjuvants for Pandemic Influenza Vaccines;3327;Part IV Novel Approaches for Vaccine Delivery;3547.1;Transcutaneous Immunization with Influenza Vaccines;3557.2;Microneedle-Based Vaccines;3778;Part V Vaccine Evaluation, Production and Distribution;4028.1;Animal Models for Evaluation of Influenza Vaccines;4038.2;Immunosenescence and Influenza Vaccine Efficacy;4198.3;Vaccines for Pandemic Influenza: Summary of Recent Clinical Trials;4368.4;Considerations for Licensure of Influenza Vaccines with Pandemic and Prepandemic Indications;4578.5;Strategies for Broad Global Access to Pandemic Influenza Vaccines;4758.6;Prioritization of Pandemic Influenza Vaccine: Rationale and Strategy for Decision Making;4989;Index;511
Compans, Richard W.
Orenstein, Walter A.
| ISBN | 9783540921653 |
|---|---|
| Artikelnummer | 9783540921653 |
| Medientyp | E-Book - PDF |
| Auflage | 2. Aufl. |
| Copyrightjahr | 2009 |
| Verlag | Springer-Verlag |
| Umfang | 512 Seiten |
| Sprache | Englisch |
| Kopierschutz | Digitales Wasserzeichen |
