The yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. It is an excellent source for all clinical physicians.

Sepsis

Infection and the Host Septic Response: Implications for Clinical Trials of Mediator Antagonism
Cytokine Markers of the Human Response to Sepsis
Heat Shock Proteins in Critical Illness: Markers of Cellular Stress or More?
A Prophylactic Approach towards Postoperative Endotoxemia
The Protective Role of Interleukin-10 in Sepsis
Treatment of Sepsis: A New Look at Prostacyclin
Nitric Oxide in Sepsis and ARDS
Is Inhibition of Nitric Oxide Synthase an Appropriate Therapeutic Target in Sepsis?
Nitric Oxide Synthase Inhibition in Septic Shock
Role of Nitric Oxide in the Regulation of Vascular Tone in Septic Shock
Administration of Methylene Blue in Septic Shock: Is it Beneficial?
Effects of Endogenous Nitric Oxide on the Pulmonary Circulation
Inhalation of Nitric Oxide in Severe ARDS
Oxygen Delivery
Nuclear Magnetic Resonance Spectroscopy: Insights into Experimental Septic Shock
Temporal Patterns of DO2 and V?O2: Predictions of Outcome and Therapeutic Goals
The Cardiac Index/Oxygen Extraction Diagram to Assess Hemodynamic Status
A New Debate: Colloid versus Colloid?
Inotropic Agents
Effects of Catecholamine Therapy on Regional Blood Flow and Tissue Oxygenation in Septic Shock
Gastric Tonometry
Regional versus Global Indicators of Tissue Oxygenation
Recent Advances in Gastric Tonometry
Management of Gastric Intramucosal Acidosis
Oxygen Carriers
The Optimal Hematocrit
The Role of Perfluorochemicals in Surgery and the ITU
The Pressor/Perfusion Effect of Diaspirin Cross-Linked Hemoglobin
Hemoglobin-based Red Cell Substitutes: Preliminary Human Studies
Cardiac Crisis
Ischemic Preconditioning: A Pronounced and Endogenous Form of Protection against Tissue Injury
The Investigation of the Patient withPalpitations
Cardiogenic Shock: How should we Revascularize?
Poisoning with Class I and IV Antiarrhythmic Agents
Perioperative Cardiac Complications
Perioperative Mortality is Reduced by Cardiovascular Optimization
Perioperative Metabolic and Hemodynamic Changes in Adults and Children
Heart-Lung Interactions
Defining the Limits of Heart-Lung Interactions
Pulmonary Hypertension in Congenital Heart Diseases
Atrial Natriuretic Peptide Modulates Pulmonary Pathophysiology
CPR
Priorities in Advanced Cardiac Life Support
Glucose Worsens and Tirilizad Improves Neurologic Outcome of CPR
Ethical Issues in Resuscitation
Acute Respiratory Failure
Acute Respiratory Failure in Infants and Children: Status Report on Gas Exchange Techniques and Outcome
Stress Proteins and Acute Lung Injury
Acute Lung Injury: Experimental Approaches to Treatment
Bedside Detection of Microvascular Injury and Edema in the Lungs
Adult Respiratory Distress Syndrome (ARDS) in Infants and Children
Risk Factors and Outcome in ARDS
Lung Mechanics
Intrinsic PEEP
Measurement of Lung Volumes and Gas Distribution during Mechanical Ventilation
Mechanical Ventilation
Protocol Control of Mechanical Ventilation in ARDS
Tracheal Gas Insufflation as an Adjunct to Conventional Ventilation
Advantages and Rationale for Pressure Controlled Ventilation
Humidification and Filtration
Use of Heat and Moisture Exchangers in Mechanically Ventilated Patients
Non-Invasive Positive Pressure Ventilation for Acute Respiratory Failure
Chronic Obstructive Pulmonary Disease
Work of Breathing in COPD
Gas Exchange in COPD
Infectious Aspects of Acute Exacerbations of COPD
Severe Infections
Antibiotic-Resistant Pathogens in the ICU: Epidemiology and Control
Severe Community-Acquired Pneumonia: A New Clinical Entity
Pneumonia: Cause or Symptom of Postinjury Multiple Organ Failure?
Candida Infections in Critically Ill Patients
Neurologic Crisis
Intracranial Pressure: Its Measurement and Treatment
New Insights in the Management of Acute Neurologic Crises using Jugular Bulb Oximetry
Bedside Estimation of Cerebral Blood Flow
Acquired Neuromuscular Abnormalities in Intensive Care Patients
Renal Failure
Continuous High Flux Dialysis (CHFD)
The Hepatorenal Syndrome
Acid-Base Balance
Use of the Anion Gap in Intensive Care and Emergency Medicine
Diagnostic Work-up of Severe Metabolic Acidosis
Intoxications
Basis of Kinetics in Clinical Toxicology
Acute Pulmonary Damage by Toxic Substances: New Aspects of Therapy
Severe Trauma
Prehospital Critical Care Services
The Prevention of Tetanus: The Story of 100 Years
Metabolic Support
Glutamine Parenteral Nutrition in Critical Illness
Catabolism - Potential for Amelioration by Growth Factors
Evaluation, Monitoring and Outcome Prediction
Small Trials in Critical Care Medicine: What can Intensivists learn from them?
Dutch Specification Study of an Intensive Care Information System
The SAPS II: A New Score with New Objectives
The MPM II System for ICU Patients
Ethics
Care of the Dying Patient
Quality of Life after Intensive Care.