The Yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

Acute Lung Injury

Acute Lung Injury: The Pathophysiology
The Role of Adhesion Molecules in Acute Lung Injury
The Critical Role of Alveolar Epithelial Barrier in Acute Lung Injury
Pulmonary Dysfunction after Remote Ischemia and Reperfusion
Surfactant Therapy in Respiratory Failure
What is the Mortality of ARDS?
Mechanical Ventilation
Mechanical Ventilation in ARDS: Interaction of Respiratory Mechanics and Gas Exchange
Mechanical Ventilation should be Individually Optimized in Patients with ARDS
Use of Pressure and Flow Waveforms to Monitor Mechanically Ventilated Patients
Patient-Ventilator Interaction: Physiology of the Triggering Function
Influence of Time on Alveolar Recruitment in Acute Lung Injury
Partial Ventilatory Support: Pathophysiologic Effects of Interfacing Spontaneous and Mechanical Ventilation
The Concept of Analgo-Sedation depends on the Concept of Mechanical Ventilation
Effect of Position and Posture on the Respiratory System
Mechanical Ventilation in Circulatory Failure
Current Status of Extracorporeal Life Support in Neonatal Respiratory Failure
Ventilatory Methods used to Wean Patients from Mechanical Ventilation
Medical Management of Post-Intubation Tracheal Stenosis
Respiratory Mechanics
Total Respiratory System, Lung and Chest Wall Mechanics in ARDS Patients
Airway Occlusion Pressure
Measurement of Respiratory Mechanics during Partial Ventilatory Support: The Interrupter Technique
Decompensated Respiratory Failure
Mask CPAP in Acute and Acute on Chronic Respiratory Failure: A Real Progress or a Dangerous Step Backwards?
Left Ventricular Function in COPD
Pulmonary Hemodynamics
Similarities between the Oxygen Sensors of the Carotid Body and the Pulmonary Vascular Bed
Therapeutic Manipulation of the Pulmonary Circulation in Acute Lung Injury
Inhaled Nitric Oxide in ARDS
Inhaled Nitric Oxide: State-of-the-Art
Inhaled Nitric Oxide in Acute Respiratory Failure
Inhaled Nitric Oxide in ARDS: Just a Replacement Therapy?
Long-term Nitric Oxide Inhalation
The Cytokine Response
The Interplay of Pro-Inflammatory Cytokines and Anti-Inflammatory Mediators during Severe Infection
Endogenous Mechanisms Regulating TNF and IL-1 during Sepsis
Proinflammatory Cytokines and the Host Response to Cancer
Oxidative Stress and Oxygen-Dependent Cytokine Production
Therapy of Sepsis
Clinical Trials of Novel Therapeutic Agents: Why did they fail?
Traditional and Novel Approaches to Interleukin-1 Antagonism
G-CSF and the Inflammatory Response in Sepsis
Antithrombin Replacement in DIC and MOF
Effects of Antibiotics on Endotoxin Release
Emergence of Bacterial Resistance during Therapy
Cardiovascular Alterations in Sepsis
"Obligatory" Role of Endothelial Cells in Regulating Myocardial Contraction?
Endothelial Modulation of Myocardial Contraction: A Novel Cardioregulatory Mechanism?
Ventricular Dysfunction during Sepsis
Towards a more Causal Treatment of Septic Cardiomyopathy
Microangiodynamic Abnormalities in Sepsis
Vascular Reactivity and Tissue Oxygenation
In Defense of Blood Pressure
Monitoring
Quantification of Left Ventricular Function Using Transesophageal Echocardiography
Transpulmonary Indicator Dilution: An Alternative Approach for Hemodynamic Monitoring
Measurement of Cardiac Output in Children
Impedance Cardiography: Non-Invasive Monitoring of Hemodynamics in the ICU
Indirect Calorimetry
Bedside Measurement of Cerebral Blood Flow: Thermodilution Techniques
Near Infrared Spectroscopy: From Clinical Research toClinical Application
Gut Function
The Impact of Critical Illness on the Gastrointestinal Tract
Barrier Function of the Intestine: Role of Immunonutrition
Gut Permeability: Mechanisms, Measurement and Clinical Applications
Possible Therapeutic Approaches to Deal with Bacterial/Endotoxin Translocation
Selective Decontamination of the Digestive Tract for the Prevention of Infection
Nosocomial Pneumonia
The Pathogenesis of Nosocomial Pneumonia in Mechanically Ventilated Patients
Nosocomial Pneumonia in the ICU - New Perspectives on Current Controversies
Invasive Methods for the Diagnosis of Ventilator- Associated Pneumonia: Is their Value Overestimated?
Renal Failure
Hemodialysis in Acute Renal Failure: Which Type of Dialysis Membrane?
Liver Dysfunction
Heterogeneity of Hepatic Perfusion in Shock
Chronic Alcoholics: High-Risk ICU Patients
Nutrition in Liver Disease
Indications and Contraindications for Liver Transplantation
Controversies in Managing Children with Fulminant Liver Failure
Severe Trauma
Trauma in the Elderly
Bacteremia, Pneumonia, and Acute Renal Failure in Trauma Patients
Head Injury
Current Concepts in Brain Resuscitation
Cerebral Perfusion Pressure and Neurointensive Care
Treatment of Post-Traumatic Brain Edema
Emergency Drug Therapy of Closed Head Injury
Monitoring Intracranial Pressure and Intracranial Compliance in Head Injury
Hypothermia for Cerebral Injury
Neurological Vignettes
Aneurysmal Subarachnoid Hemorrhage
Guillain-Barré Syndrome in the 1990's
Emergencies
Treatment of Hypovolemic Shock
Hypertonic Solutions in Emergency Medicine
Dopaminergic Drugs in Cardiovascular Emergencies
Emergency Management of Broad QRS Complex Tachycardia
Emergency Medical Services forChildren
Heatstroke: Marathons to Mecca
ICU Management
Continuous Quality Improvement
Rationing and Triage
Neural Networks in Critical Care.